Molecular Formula | C11H20N2O3 |
Molar Mass | 228.29 |
Density | 1.123g/cm3 |
Melting Point | 158-160℃ |
Boling Point | 384.4°C at 760 mmHg |
Flash Point | 186.3°C |
Vapor Presure | 4.1E-06mmHg at 25°C |
pKa | 16.40±0.20(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.498 |
MDL | MFCD02180953 |
Hazard Symbols | Xi - Irritant |
Safety Description | S24/25 - Avoid contact with skin and eyes. |
HS Code | 29333990 |
Hazard Class | Irritant |
Downstream Products | tert-Butyl 4-(aminocarbothioyl)tetrahydropyridine-1(2H)-carboxylate 1-Boc-4-(aminomethyl)piperidine |
N-tert Butoxycarbonyl-4-piperidone (Boc piperidone) is an organic compound with the chemical formula C11H20N2O3.
Boc piperidone is a derivative of piperidine acetone, obtained by introducing a tert butoxycarbonyl group (Boc group) onto the piperidine ring. It is a colorless to light yellow solid commonly used as an intermediate in organic synthesis.
Boc piperidone has stable chemical properties and is easily soluble in commonly used organic solvents such as dimethylformamide (DMF), dichloromethane (DCM), and ether. It is commonly used as a basic reagent, carbonylation reagent, and nucleophilic reagent in chemical reactions.
Boc piperidone has extensive applications in organic synthesis. It can be reduced to the corresponding piperidine acetone or obtained by decarboxylation to obtain the corresponding piperazine. In drug synthesis, Boc piperidone is often used as an important intermediate for the preparation of certain antidepressant and spasmodic drugs. In addition, it is also used to synthesize various biologically active molecules, such as protein kinase inhibitors and anticancer drugs.
Overall, Boc piperidone is an important organic compound with a wide range of applications, which is of great significance for organic synthesis and drug research.